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This version of NSU News has been archived as of February 28, 2019. To search through archived articles, visit nova.edu/search. To access the new version of NSU News, visit news.nova.edu.
This version of SharkBytes has been archived as of February 28, 2019. To search through archived articles, visit nova.edu/search. To access the new version of SharkBytes, visit sharkbytes.nova.edu.
NSU Researcher Authors Book Chapter
Appu Rathinavelu, Ph.D.
Appu Rathinavelu, Ph.D., associate dean for institutional planning and development at NSU’s College of Pharmacy and executive director of NSU’s Rumbaugh-Goodwin Institute for Cancer Research, co-authored a chapter in the soon-to-be published book, Prostate Cancer – Advances in Diagnosis, Treatment and Care of Patients. Rathinavelu drafted the chapter, titled “Key genes in prostate cancer progression: Role of MDM2, PTEN and TMPRSS2-ERG fusions” while he was on Fulbright sabbatical in India.
The book chapter addresses various cellular and molecular events that can trigger the onset of prostate cancer and transform the disease to become more aggressive. It describes the impact of genes on various cellular pathways and regulatory mechanisms that are part of the prostate cancer development. It also discusses the pathological roles and the potential diagnostic and therapeutic applications of these genes, which are highly expressed in prostate cancer when compared to other cancer types. The presence of these genes and the gene defects are frequently linked to growth, progression, metastasis, invasiveness, and resistance in prostate cancers.
The co-author of this book chapter is Arkene Levy, Ph.D., a faculty member of the Department of Medical Sciences at the University of West Indies. Levy is currently conducting her sabbatical at NSU’s Rumbaugh-Goodwin Institute for Cancer Research.