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Math Colloquium Series to Discuss Mathematical Modeling for Medical Tissue Engineering, Feb. 23

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Join NSU’s Halmos College of Natural Sciences and Oceanography for the next Mathematics Colloquium Series event, which will explore the intersection of mathematics and biomedical engineering.

Manuel Salinas, Ph.D., Assistant Professor, NSU

Manuel Salinas, Ph.D., Assistant Professor, NSU

“Heart Valve Tissue Engineering: Mathematical Modeling for Bioreactor Studies”

Mathematics Colloquium Series

Speaker: Manuel Salinas, Ph.D., Assistant Professor, NSU

Thursday, February 23

Noon–1:00 p.m.

Reception: 11:30 a.m. | Department of Mathematics Suite | Mailman-Hollywood Building, Second Floor

Lectures: Noon–1:00 p.m. | Mailman-Hollywood Building, Second Floor Auditorium

These talks are free and open to the public.


About the Talk

Mechanical conditioning has been shown to promote tissue formation in a wide variety of tissue engineering studies, but the underlying mechanisms by which external mechanical stimuli regulate cells and tissues are not fully understood. This is particularly relevant in the area of heart valve tissue engineering (HVTE) due to the intense hemodynamic environments that surround native valves. Some studies suggest that oscillatory shear stress (OSS) caused by steady flow and scaffold flexure play a critical role in engineered tissue formation derived from bone marrow derived stem cells (BMSCs). In addition, scaffold flexure may enhance the transport of nutrients such as glucose and oxygen. This talk will explore a recent study that computationally quantified the a) magnitude of fluid-induced shear stresses; b) the extent of temporal fluid oscillations in the flow field using an oscillatory shear index (OSI) parameter, and c) glucose and oxygen mass transport profiles. read more

About the Speaker

Manuel Salinas received his B.S. (2009), M.S. (2011), and Ph.D. (2014) in Biomedical Engineering from Florida International University. He was a post-doctoral fellow at Harvard Medical School before joining NSU’s College of Engineering and Computing. He has published several papers in academic journals relating to heart valve tissue engineering studies. His research areas include vascular tissue engineering, artificial organs, and cardiovascular biomechanics. In addition, he enjoys collaborating on projects related to computational fluid dynamics, fluid structure interactions, algorithm optimization, finite element/volume analysis, computer-aided design, and steady and transient data visualization.

About the Series

Hosted by NSU’s Halmos College of Natural Sciences and Oceanography Department of Mathematics, the Mathematics Colloquium Series aims to increase awareness of the importance of mathematics and applications in daily life. The series also gives mathematics faculty members and students the opportunity to discuss independent research and share their passion for the subject. For more information, contact Jeffrey W. Lyons, Ph.D., associate professor, at (954) 262-7931.